



ARCHITECT OF FRONTIER LIQUIDITY
- LEADERSHIP
- …
- LEADERSHIP



ARCHITECT OF FRONTIER LIQUIDITY
- LEADERSHIP
- …
- LEADERSHIP

INVESTMENT
Building the Markets Before They Exist
Investment
Leesa Soulodre is an investor, entrepreneur, and architect of emerging markets.
For more than 25 years, she has worked at the intersection of capital, technology, regulation, and institutional transformation—helping investors, governments, corporations, and founders navigate periods of profound economic change.
Her investment philosophy is built on a simple observation:
The most valuable markets of the future are rarely created by technology alone.
They emerge when technological breakthroughs converge with regulatory change, geopolitical priorities, resource constraints, and institutional capital.
Throughout her career, Leesa has focused on identifying these inflection points early—before they become obvious, before capital crowds into the sector, and before markets fully price the opportunity.
Today, that thesis forms the foundation of R3i.
R3i
Leesa is the Founder and Managing Partner of R3i, a global investment and venture creation platform operating across the United States, Luxembourg, and Singapore.
R3i combines proprietary intelligence, venture creation, strategic transaction execution, and multi-jurisdictional capital architecture to help build and scale the technologies shaping future economic systems.
The platform works with sovereign wealth funds, family offices, institutional investors, government agencies, strategic corporates, and founders seeking exposure to transformational opportunities emerging from structural change.
Rather than simply allocating capital, R3i focuses on identifying, building, and accelerating markets before they become mainstream investment categories.
Investment Thesis
The next generation of wealth creation will be driven by technologies and infrastructure that strengthen sovereign capability, economic resilience, and strategic independence.
As governments establish new frameworks around artificial intelligence, healthcare, climate resilience, compute sovereignty, critical infrastructure, and space governance, trillions of dollars of capital are being redirected toward entirely new categories of economic activity.
Leesa's investment approach seeks to identify where these forces converge and where regulatory transformation creates long-term competitive advantage.
The objective is not to follow markets.
It is to understand how new markets are formed.
Areas of Focus
Artificial Intelligence & Digital Trust
AI is becoming foundational infrastructure for governments, enterprises, and societies.
Leesa invests in platforms enabling trusted AI deployment, governance, compliance, verification, reputation intelligence, and enterprise-scale adoption.
Defence, Security & Sovereign Capability
National resilience increasingly depends on technological advantage.
Investment areas include dual-use technologies, advanced sensing, cyber resilience, secure communications, critical infrastructure protection, and systems supporting strategic independence.
Space Infrastructure & Emerging Space Economies
Space is evolving into a strategic economic domain.
Leesa focuses on technologies enabling orbital infrastructure, resource intelligence, quantum-enabled sensing, advanced navigation, and sovereign participation in emerging space ecosystems.
Sovereign Compute & Frontier Technologies
Computational power is becoming a strategic national asset.
Investment areas include quantum computing, advanced materials, next-generation computing architectures, AI infrastructure, and technologies supporting long-term technological sovereignty.
Precision Health & Human Performance
Healthcare is shifting from treatment to prediction.
Leesa invests in technologies advancing diagnostics, neurodegenerative disease detection, personalized medicine, and healthcare system transformation.
Climate, Water & Resource Infrastructure
Long-term prosperity depends on resource security.
Investment focus includes energy storage, water intelligence, industrial decarbonization, climate adaptation, and infrastructure supporting resilient economic growth.
Selected Investments & Ventures
Representative companies and platforms include:
* Quantum Brilliance – Room-temperature diamond quantum computing
* MGA Thermal – Long-duration thermal energy storage
* ViewMind – AI-powered neurodegenerative disease diagnostics
* StratifiCare – Predictive healthcare and clinical intelligence for Oncology and Infectious Diseases
* Soliddd – Smart glasses to solve for macular degeneration
* Asima Health – Novel Cancer Screening Diagnostics
* Flexpenser – A non-penetrable seal, protecting your product from oxidation, bacteria, and other contaminants.
* AquaTasker – Water intelligence and infrastructure analytics for Data Centres and Markets
* AIComply – AI governance and regulatory automation
* Kloutify.ai – AI discoverability and reputation intelligence
* iProofD – Intellectual property intelligence and commercialization
Experience
Leesa has participated in the acceleration, investment, and growth of more than 350 venture-backed companies globally.
Her experience spans venture capital, institutional investment, innovation ecosystems, reputation economics, responsible investment, AI governance, healthcare, climate technology, and frontier technologies.
She has advised more than 400 multinational corporations across 19 industries and has served as a General Partner, Venture Partner, Entrepreneur-in-Residence, Investment Committee Member, and strategic advisor across multiple investment platforms.
Her work has supported founders, investors, governments, and corporations across Europe, Asia-Pacific, the Middle East, North America, and Australia.
Governance & Leadership
Leesa has held leadership and advisory roles across investment, technology, governance, and academic institutions, including:
* AI Asia Pacific Institute
* Mandalay Venture Partners
* Omusubi Fund
* Singapore Management University
* SMU Cox School of Business
* IE Business School
* TRIUM Global Executive MBA Angels Network
She is also the Godmother of Masters & Robots, one of Europe's leading forums exploring the future relationship between humans, technology, and work.
The Long View
Leesa's work is guided by a belief that the most significant investment opportunities emerge during periods of structural change.
As artificial intelligence, sovereign compute, healthcare transformation, climate adaptation, resource security, and space infrastructure redefine the global economy, she continues to focus on building the bridges between breakthrough innovation and long-term capital.
The goal is not simply to invest in the future.
It is to help build the systems through which the future is financed, governed, and scaled.
At R3i, we encourage our community to
"Think a New Thought"
Source: Issimo Agency
Douglas L. Jones, Former Director
Advanced Digital Science Centre
University of Illinois Urbana Champaign
"Leesa is a serial entrepreneur and intrapreneur, who brings a broad range of perspectives to bear. She has worked in innovation leadership roles in a variety of industries - and from very large to startup companies, as well as in mentoring and consulting roles!
You can find a short biography online but it doesn’t fully convey Leesa’s dynamism and freewheeling idea generation coupled with prompt and thorough execution."
Ramzi BEN ROMDHANE
Managing Director
Digital Transformation Group
Nissan Renault
"Leesa Soulodre is a collaborator, pioneer, and builder. She is a knowledgeable and seasoned technology entrepreneur, well-informed about her sector’s cutting-edge innovations and competitive strategy. As a collaborator, we have worked on numerous complex topics including analytics and machine learning applications for predictive software fault resolution of autonomous vehicles and digital risk transformation. Leesa continues to support me with the devil's advocacy that I need to find even greater creative solutions to very complex problems. She shows strong business and industry acumen, underwritten by a strong technical pragmatism and a unique ability in leveraging her extensive network.
Leesa has grit, resilience, a strong curiosity and learning appetite, and a passion for human purpose! She infuses energy and performance into everything she touches. As a pioneer and builder, she is passionately committed to making a difference."Oliver Kysela
CFO Endota
Behind Leesa's charming and sophisticated disposition is a highly motivated, respected and exceptionally energetic professional.
To me, her competitive advantage is that her decision-making and advice is generated from strong and balanced principles that consider all facets of future value, and not just short-term success at any cost."
Alexander Post, Cofounder, and Chief Innovation Officer
MGA Thermal
"Leesa Soulodre works with my deep-tech start-up company, as both a mentor and Advisory Board member. During this time, the energy, knowledge, and connections that Leesa has brought to the team have been absolutely invaluable. Professionally, Leesa is the most driven individual I've ever met, with unparalleled enthusiasm and an ability to make connections. This is backed up by her deep knowledge of the global startup investment landscape, a keen mind for commercial strategy and an amazing willingness to help.
Personally, Leesa is both easy to get along with and tenacious, continuously mentoring all members of our team and fostering a great innovative atmosphere, and never failing to bring a voice of ambition, cooperation, and confidence to the table. On both levels, I cannot speak highly of her enough."
Rachel Hong, CEO and Cofounder, Meracle Health
"Our one on one coaching with Leesa at the IoT Tribe Accelerator helped to propel us forward in multiple aspects of our business. Through her vast network in the Medtech space, she has connected us to relevant partners and advisors with a broad range of capabilities. She has been instrumental in helping us articulate our market entry strategy and expand our access to the European market. True to her mission of founders first, the direction she provided focused on adding value by achieving critical milestones."
Dr. Anthony Chua, Stratificare, Inc.
"As a hands-on venture builder and founder Coach, Leesa has helped us to raise capital,
secure advanced reimbursement from the world's largest insurance network, and through he
extensive networks, accelerated our expansion into Latin America.
I have not seen someone as willing to roll up her sleeves to help local DeepTech startups as Leesa.
She brings irreplaceable contributions to our Board of Advisors, and to the local DeepTech startup ecosystem of Singapore."

R3i invests globally in highly scalable IP-based emerging technology companies with a tangible ESG product impact and artificial intelligence advantage.
Stay close to the frontier.
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